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Table 3 Percentage frequencies of polymorphisms in the caprine Prnp open reading frame in UK farms.

From: Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom

Herd

A$

B$

C

D

E$

F

G

H

I

X

J$

K

L

M

P

Q

R

S

T

Breed Category

Dairy

Dairy

Meat

Fiber

Fiber

Meat

Meat

Other

Breed

S, T, A, N

S, A

S, T

S, T

S

S

S, A

S, T, A, N

S

S, T

S, B

Ag

Ag

Ag, C, B

B

B

B

GG

F

Number

323

188

20

39

91

35

23

29

48

41

97

29

22

35

103

21

29

12

10

wt-P & wt-S

62.9

50.8

50

60.2

59.3

57.1

76.2

96.6

61.5

75.7

63.4

96.6

95.5

75.7

52.4

57.1

69

16.7

100

R101

-

0.5

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

S127

5.3

25.5

10

-

3.3

4.3

4.3

-

-

2.4

3.1

-

-

-

-

2.4

-

-

-

M142

29.1

23.2

32.5

37.2

33

27.1

15.2

-

37.5

19.5

20.8

1.7

-

1.4

19.4

2.4

-

-

-

R143

-

-

-

-

-

-

-

3.4

-

-

-

1.7

4.5

8.6

2.9

2.4

12

-

-

S146

-

-

7.5

-

-

-

-

-

-

-

4.1

-

-

4.3

23.3

33.3

19

-

-

H154

-

-

-

-

-

-

-

-

-

-

-

-

-

1.4

0.5

-

-

-

-

Q211

1.9

-

-

1.3

3.3

8.6

4.3

-

1

2.4

6.8

-

-

-

-

2.4

-

50

-

L218

-

-

-

-

-

-

-

-

-

-

-

-

-

8.6

1.5

-

-

-

-

K222

0.8

-

-

1.3

1.1

2.9

-

-

-

-

1.6

-

-

-

-

-

-

33.3

-

  1. Breeds: A = Alpine, Ag = Angora, B = Boer, C = Cashmere, GG = Golden Guernsey, N = Anglo-Nubian, S = Saanen, T = Toggenburg, F = Feral; number = number of animals, for calculation of allele frequency this is doubled to get number of chromosomes. For codon 101 only 2350 chromosomes were recorded and for codon 127 only 2362. X represents five farms each ≤ 12 animals. $scrapie-affected herds.
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Veterinary Research

ISSN: 1297-9716