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Table 3 Bioassay of different localizations of bovine small intestine in bovine transgenic mice (Tgbov XV): results (revealed by PTA-Immunoblot), transmission rates and incubation periods

From: BSE infectivity in jejunum, ileum and ileocaecal junction of incubating cattle

Months p.i.

Cow

Localization

  

Jejunum A

Jejunum B

Ileum

Ileocaec.

 

IT 14

0/10

--

0/14

--

9/13

280 ± 41

0/15

--

8

IT 20

0/14*

--

0/13

--

8/11

334 ± 61

0/15*

--

 

IT 39

1/14*

502

0/12*

--

7/11*

310 ± 49

0/12

--

 

IT 55

2/10*

379, 522

0/12

--

7/9

332 ± 47

3/13

442, 517, 582

12

IT 01

0/14*

--

3/10

407, 432, 600

12/13

305 ± 45

14/15

315 ± 40

 

IT 16

0/13

--

0/12

--

6/11

412 ± 31

1/10

395

 

IT 06

0/12

--

1/13

375

10/10

279 ± 47

12/12

277 ± 39

 

IT 57

0/15

--

2/10

393, 428

11/11

260 ± 55

9/11

297 ± 64

 

IT 07

0/14*

--

0/15

--

0/12*

--

0/9

--

16

IT 28

0/11

--

0/11

--

0/11

--

0/12

--

 

IT 46

0/11

--

0/12

--

0/10

--

0/12

--

 

IT 65

0/12

--

0/11

--

11/14*

319 ± 41

13/13*

349 ± 53

20

IT 10

0/13

--

2/15

363, 408

0/11*

--

0/9

--

 

IT 17

0/12*

--

0/10

--

0/15*

--

12/12

311 ± 33

 

IT 50

0/12*

--

0/14*

--

11/13

353 ± 57

0/12*

--

 

IT 60

1/12

391

0/9

--

11/12

345 ± 37

0/12

--

  1. The first line indicates the number of positive tested mice/total number of mice, the second line indicates the mean incubation period in days post infection
  2. * augmented groups - additional inoculations after heating the inoculum to 70°C for 10 min