Higher whole-blood selenium is associated with improved immune responses in footrot-affected sheep

Table 1 Whole-blood selenium concentrations in healthy and footrot (FR) affected sheep treated with selenium (FR-Se) or saline (FR-Sal)*

	Median whole-blood Se (range); ng/mL
Month of Treatment	Healthy	FR-Se	FR-Sal
0	250 (187 351)^a	199 (109 278)^b	202 (111 323)^b
3	245 (145 340)^a	261 (189 317)^a	199 (110 295)^b
6	274 (180 396)^b	302 (267 403)^a	268 (176 408)^b
15	230 (165 302)	288 (157 416)	237 (104 344)

*Adapted from Hall et al. [12]. Footrot-affected sheep (n = 38) were alternately randomized into two treatment groups and at 1-month intervals injected subcutaneously with 5 mg of Se (FR-Se) or with 1-mL of saline solution (FR-Sal) for 15 months. A control group of 19 healthy sheep without FR received no injections. There were 19 sheep/group at 0 and 3 months, 18 to 19 sheep/group at 6 months, and 9 to 14 sheep/group at 15 months.
^{a, b}Medians with different superscripts within month are different (P < 0.05).

ISSN: 1297-9716