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Table 2 Epidemiological and clinical characteristics of O104:H4 Agg-VTEC infections as compared to O157:H7 AE-VTEC infections

From: O157:H7 and O104:H4 Vero/Shiga toxin-producing Escherichia coli outbreaks: respective role of cattle and humans

 

AE-VTEC O157:H7

Agg-VTEC O104:H4

Incidence of sporadic cases

Third bacterial cause of diarrhoea in developed countries

Extremely rarely reported

Outbreaks

Frequent (from a few to > 6000 cases)

One outbreak (almost 4000 cases)

Age distribution

Young children (elderly)

Middle aged adults

Gender distribution

Equal

Predominance of female

Incubation

1 to 9 days (average 3-5 days)

8 days (interquartile range 7 to 9 days)

Progression to HUS

7-10%

> 20%

Mortality

0.5%

1.4%