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Table 3 Analysis of boTLR1 SNP genotypes by CM and milk productivity traits over the first three lactations.

From: Identification of single nucleotide polymorphisms in the bovine Toll-like receptor 1 gene and association with health traits in cattle

SNP

Gen.

n =

P% with CM1

Mean CM rate2

P = 3

Median SCC4

P = 3

Mean 305 d milk yield4

P = 3

Mean milk fat (%)4

P = 3

Mean milk protein (%)4

P = 3

tag-79 T > G

TT

78*

58%

0.40 (± 0.11)

 

1.96 (± 0.63)

 

7868 (± 1181)

 

4.15 (± 0.41)

 

3.28 (± 0.19)

 
 

TG

122*

60%

0.75 (± 0.18)

< 0.05

1.85 (± 0.61)

-

8058 (± 1139)

-

4.02 (± 0.38)

< 0.05

3.2 (± 0.17)

< 0.01

 

GG

46*

70%

0.70 (± 0.24)

-

1.98 (± 0.67)

-

7983 (± 1273)

-

3.89 (± 0.41)

< 0.01

3.16 (± 0.18)

< 0.001

+1762A > G

AA

33

63%

0.69 (± 0.27)

-

1.96 (± 0.64)

-

8101 (± 1106)

-

3.95 (± 0.41)

-

3.19 (± 0.18)

-

 

GA

57

61%

0.66 (± 0.18)

-

1.89 (± 0.69)

-

8067 (± 1330)

-

4.04 (± 0.45)

-

3.21 (± 0.2)

-

 

GG

35

59%

0.38 (± 0.16)

 

1.90 (± 0.62)

 

8239 (± 1185)

 

4.05 (± 0.38)

 

3.25 (± 0.16)

 

+2463 C > T

CC

64

67%

0.70 (± 0.24)

-

1.95 (± 0.66)

-

7841 (± 1067)

-

4.02 (± 0.45)

-

3.19 (± 0.18)

< 0.05

 

CT

102

61%

0.70 (± 0.14)

< 0.05

1.90 (± 0.63)

-

8137 (± 1206)

-

3.98 (± 0.45)

-

3.18 (± 0.2)

< 0.05

 

TT

59

59%

0.39 (± 0.11)

 

1.88 (± 0.63)

 

7940 (± 1262)

 

4.13 (± 0.38)

 

3.27 (± 0.18)

 
  1. Abbreviations: Gen. = genotype, P% = population percentage, CM = clinical mastitis, SCC = somatic cell count. * Numbers from tagged SNP +798 C > T in Table 2. 1No significance was detected between genotypes by Chi^2 odds ratio test. 2Mean ± 95% confidence interval given in column parentheses. 3P values analysed by ANOVA and Tukey's multiple comparisons, showing only results tested against the underlined (lower CM rate) genotype; - (dash) denotes no significance. 4Standard deviation from the mean given in column parentheses.