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Figure 3 | Veterinary Research

Figure 3

From: Protection from reinfection in “Candidatus Mycoplasma turicensis”-infected cats and characterization of the immune response

Figure 3

Relative expression levels of TNF- α (A), IFN- γ (B), IL-4 (C), IL-12 (D) and IL-10 (G) after CMt inoculation on day 0 in cats from group A (black squares) and group B (open squares). The Th2/Th1 ratio is expressed as the IL-4/IL-12 ratio (E) and the IL-4/IFN-γ ratio (F). Cytokine mRNA expression levels were measured by real-time Taqman® PCR and were normalized to the expression levels of two housekeeping genes (ABL and YWHAZ) at each time point. The values shown represent the mean and standard deviation for each group of cats. The arrow indicates the onset of bacteremia and the gray box indicates the peak bacteremia for the cats in group B. Relative expression levels were tested for statistical differences between groups by the Mann–Whitney U-test (asterisks indicate statistically significant differences; P < 0.05).

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