Figure 2From: High rate of transplacental infection and transmission of Neospora caninum following experimental challenge of cattle at day 210 of gestationNeospora caninum specific placental lesions following subcutaneous challenge of pregnant cattle at day 210 of gestation. a: 28 dpi. A focus of necrosis (arrowheads), mainly affecting foetal mesenchyme but involving also adjacent areas of maternal caruncular septa. HE. ×100. b: 28 dpi. Serum leakage and formation of fibrin (red) is showed between the foetal villus (right) and the maternal septa (left). MSB. ×200. c: 42 dpi. Focus of necrosis affecting both maternal and foetal tissue. There is a marked mononuclear cell inflammation in the periphery of the focus (arrowheads). HE. ×100. d: 42 dpi. Focus of mononuclear inflammation (arrowhead) at the tunica intima and media of an arteriole located at the maternal caruncular septa. HE. ×200. e: 56 dpi. Prominent thickening and hypercellularity of the maternal caruncular septa (arrowheads). Atrophy and loss of trophectoderm of foetal villi adjacent to the thickened area (white arrowheads). HE. ×40. f: 56 dpi. Proliferation of connective tissue (green) in a thickened area of the maternal caruncular septa. Gomori Trichrome. ×40.Back to article page