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Table 1 Grading of the pulmonary lesions.

From: Interstitial lung disease associated with Equine Infectious Anemia Virus infection in horses

Type of lesion

 

Number of cases

EIAV pos

EIAV neg

[A] Lymphocyte infiltration

Absence:

14

11

Presence:

65

3

 

Grade:

  

[B] (Peri)bronchiolar inflammation

0

15

11

I

41

3

II

17

0

III

5

0

IV

1

0

[C] Thickness of the septa

0

24

13

I

34

1

II

21

0

III

0

0

 

Histological score* [(B + C)/2]

No lesions

0 (0–0.4)

13

11

Mild lesions

I (0.5-1.4)

35

3

Moderate lesions

II (1.5-2.4)

27

0

Severe lesions

III (>2.4)

4

0

 

Mean score:

1.09

0.17

  1. Pulmonary lesions have been blindly observed and graded according to their severity from EIAV-positive (EIAVPOS) and EIAVnegative (EIAVNEG) horses. [A] described the presence of infiltrating lymphocytes. [B] described the type and the severity of (peri) bronchiolar inflammation; [C] described the thickness of the septa and its severity; * total histological score was calculated using the [(B + C)/2] formula. The histological score allows the ranking of the pulmonary disease where 0 to 0.4 means no lesions, 0.5-1.4 mild lesions, 1.5-2.4 moderate lesions and >2.4 severe lesions.