Gene symbol | Gene description | Fold change | |
---|---|---|---|
3Â h | 6Â h | ||
Transcription and activation pathways | Â | Â | |
  NFKBIA | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.60 | 4.53 |
  BIRC3 | Baculoviral IAP repeat-containing protein 3 | 3.10 | 3.19 |
  ZNFX1 | NFX1-type zinc finger-containing protein 1 |  | 3.11 |
  ZNHIT3 | Zinc finger HIT domain-containing protein 3 | 2.48 | 3.08 |
  IKBKAP | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | 2.52 | 2.33 |
  TRIM21 | Tripartite motif-containing protein 21 | 1.61 | 2.26 |
  CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.02 | 1.60 |
  NFKB2 | Nuclear factor of κ light polypeptide gene enhancer in B-cells 2 | 1.78 | 1.94 |
  JAK2 | Janus kinase 2 | 1.90 | 1.85 |
  DUSP1 | Dual specificity phosphatase 1 |  | 1.85 |
  FOS | V-fos |  | -2.01 |
  PLK2 | Serum-inducible kinase, transcript variant 1,PLK2 | -1.50 |  |
Cytokines and chemokines, growth factors | Â | Â | |
  CCL5 | RANTES | 7.10 | 20.52 |
  CCL20 | Chemokine (C-C motif) ligand 20 | 19.42 | 19.37 |
  CXCL8 | Chemokine (C-X-C motif) ligand 8, Interleukin-8 | 8.53 | 13.96 |
  CXCL5 | Chemokine (C-X-C motif) ligand | 4.75 | 7.96 |
  CCL2 | Chemokine (C-C motif) ligand 2 |  | 6.38 |
  CXCL2 | Chemokine (C-X-C motif) ligand 2 |  | 5.06 |
  CXCL1 | Chemokine (C-X-C motif) ligand 1 | 4.93 |  |
  IL6 | Interleukin 6 | 6.64 | 4.85 |
  CXCL3 | Chemokine (C-X-C motif) ligand 3 | 3.15 | 3.60 |
  IL1B | Interleukin 1, beta | 5.01 | 3.32 |
  IFNB | Interferon beta precursor | 4.89 | 3.25 |
  TNFSF13B | Tumor necrosis factor (ligand) superfamily, member 13 (BAFF) | 2.96 |  |
  IL2 | Interleukin 2 | 4.30 | 2.86 |
  CCL16 | Chemokine (C-C motif) ligand 16 | 2.60 | 2.77 |
  CSF2 | Colony stimulating factor 2 (granulocyte-macrophage) | 1.69 | 2.10 |
  IL23A | Interleukin 23, alpha subunit p19 |  | 2.06 |
  CTGF | Connective tissue growth factor | -1.92 |  |
  TGFB2 | Transforming growth factor beta-2 precursor |  | -1.46 |
Type I IFN-related genes | Â | Â | |
  IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 3.02 | 7.92 |
  MX1 | Myxovirus (influenza virus) resistance 1 | 1.84 | 2.93 |
  IFIH1 | Interferon induced with helicase C domain 1 | 2.65 | 4.10 |
  ISG15 | ubiquitin-like modifier | 2.46 | 3.69 |
  GBP1 | Interferon-induced guanylate-binding protein 1 | 2.17 | 3.56 |
  TNFSF10 | Tumor necrosis factor ligand superfamily member 10 (TRAIL) | 2.02 | 3.13 |
  IFI44 | Similar to Interferon-induced protein 44 |  | 3.23 |
  OAS1 | 2′-5′-oligoadenylate synthetase 1 | 1.61 | 3.15 |
  IFI27L1 | Interferon alpha-inducible protein 27-like protein 1 |  | 2.88 |
  IRF7 | Interferon regulatory factor 7 | 1.45 | 2.75 |
  TRIM21 | Tripartite motif-containing protein 21 | 1.61 | 2.26 |
  GVIN1 | GTPase, very large interferon inducible 1 |  | 2.21 |
  STAT2 | Signal transducer and activator of transcription 2 |  | 2.01 |
  STAT1 | Signal transducer and activator of transcription 1 |  | 1.96 |
  IRF2 | Interferon regulatory factor 2 |  | 1.84 |
Immune defense response | Â | Â | |
  NOS2A | Nitric oxide synthase 2A (inducible) | 5.57 | 7.45 |
  S100A8 | Calcium-binding protein A8, calgranulin A | 2.87 | 7.00 |
  CFB | Complement factor B | 3.39 | 5.02 |
  S100A9 | Calcium-binding protein A9, calgranulin B | 2.40 | 4.59 |
  CD83 | Cell surface protein HB15 | 5.50 | 3.40 |
  C2 | C2 Complement component 2 | 1.79 | 2.64 |
  ICAM1 | Intercellular adhesion molecule 1 | 2.50 |  |
  LTF | Lactotransferrin |  | 2.47 |
  PLAT | Plasminogen activator, tissue type | 1.93 | 2.11 |
  PLAUR | Urokinase plasminogen activator surface receptor | 2.11 | 1.96 |
  CAMP | Cathelicidin antimicrobial peptide |  | 1.89 |
  TLR4 | Toll-like receptor 4 | 1.62 | 1.81 |
  MMP9 | Matrix metallopeptidase 9 |  | 1.77 |
  CD74 | Major histocompatibility complex, class II invariant chain |  | 1.75 |
  BNBD10 | Beta-defensin 10 | 1.59 | 1.67 |
Stress response | Â | Â | |
  SOD2 | Superoxide dismutase 2 | 3.19 | 5.05 |
  SGK1 | Serum/glucocorticoid regulated kinase 1 | 1.81 | 4.79 |
  PARP14 | Poly (ADP-ribose) polymerase family, member 14 |  | 2.95 |
Cell growth and cycle, apoptosis | Â | Â | |
  IGFBP3 | Insulin-like growth factor binding protein-3 | 2.38 | 5.27 |
  EIF4E | Translation initiation factor 4E | 2.32 | 5.20 |
  CASP4 | Caspase-4 Precursor | 1.60 | 3.04 |
  CASP8 | Caspase-8 precursor | 1.58 | 2.29 |
  IER3 | Immediate early response 3 | 2.09 |  |
  TNFRSF6 | TNF receptor superfamily, member 6 (FAS) | 1.82 | 1.86 |
  CDK2AP1 | Cyclin-dependent kinase 2 associated protein 1 |  | -1.66 |
  EI24 | Etoposide-induced protein 2.4 homolog |  | -1.65 |