Comparative genome sequencing identifies a prophage-associated genomic island linked to host adaptation of Lawsonia intracellularis infections

Table 4 Single nucleotide substitutions in passage 10 and passage 60 of the porcine L. intracellularis isolate PHE/MN1-00

Gene locus (Position)	Description	Amino acid change		Substitution
		Passage 10	Passage 60
Chromosome
LI0064 (86 203)	Transcriptional regulator	Glutamic acid	Lysine	Non-synonymous
LI0064 (86 203)	Transcriptional regulator	(G AA)	(A AA)	Non-synonymous
LI0473 (577°207)	DNA methylase	Lysine	Glutamic acid	Non-synonymous
LI0473 (577°207)	DNA methylase	(A AA)	(G AA)	Non-synonymous
LI0532-LI0533 (651°651)	Intergenic region
LI0905 (1°129°621)	DNA-directed RNA polymerase	Lysine	Glutamic acid	Non-synonymous
LI0905 (1°129°621)	DNA-directed RNA polymerase	(A AG)	(G AG)	Non-synonymous
Plasmid C
LIC103 (190°854)	Methyl-accepting chemotaxis	Cysteine	Cysteine	Synonymous
		(TGC)	(TGT)

Bold underline letters: Single nucleotide substitution from passage 10 to passage 60.

ISSN: 1297-9716