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Table 1 Presence of BPV-1 and immunohistochemical expression of BAG3 in equine sarcoids

From: BAG3 protects Bovine Papillomavirus type 1-transformed equine fibroblasts against pro-death signals

Samples*

Clinical type

BPV-1 DNA

BAG3 immunohistochemical staining**

T1

Nodular

+

+++

T2

Mixed

+

+/−

T3

Verrucous

+

++

T4

Fibroblastic

+

++

T5

Flat

+

+++

T6

Verrucous

+

++

T7

Mixed

+

++

T8

Flat

+

+/−

T9

Fibroblastic

+

n.a.

T10

Verrucous

+

+++

T11

Verrucous

+

+++

T12

Nodular

+

++

T13

Verrucous

+

n.a.

T14

Nodular

+

+

T15

Mixed

+

+

N1

Normal skin

+

+

N2

Normal skin

n.a.

+/−

N3

Normal skin

n.a.

+/−

N4

Normal skin

n.a.

+/−

N5

Normal skin

n.a.

+/−

  1. *T: tumour sample; N: normal skin sample.
  2. **Immunoreactivity scoring was determined by two observers. The intensity of immune labelling for each specimen was scored on a four-tiered scale: +/−, very weak signal; +, weak signal; ++, moderate signal; +++, strong signal; n.a., not assessable.