From: Innate sensing of viruses by pattern recognition receptors in birds
Pattern recognition | Human | Origin of ligand | Chicken | Duck/Goose | Origin of ligand |
---|---|---|---|---|---|
receptor (PRR) | Â | Â | Â | Â | Â |
Membrane-bound PRR (TLR) | |||||
On plasma membrane | TLR1/6/10 | Bacteria | TLR1La TLR1Lb | Not reported | Unknown; bacteria |
TLR2 | Bacteria; Fungus; Parasites; Virus | TLR2a TLR2b | Present in duck; Not reported in goose | Unknown; Bacteria | |
TLR4 | Bacteria; Fungus; Parasites; Virus | Present | Present | Unknown | |
TLR5 | Bacteria | Present | Not reported in duck; Present in goose | Bacteria | |
TLR11 | Bacteria; Parasites | Absent | Not reported | Unknown | |
Absent | Â | TLR15 | Not reported in duck; Present in goose | Bacteria; Virus | |
In intracellular vesicles | TLR3 | Virus | Present | Present in duck; Not reported in goose | Virus |
TLR7 | Virus | Present | Present | Virus | |
TLR8 | Virus | Pseudogene | |||
TLR9 | Virus; Bacteria; Parasites | Absent | |||
Absent | Â | TLR21 | Not reported | Unknown | |
Cytoplasmic PRR | |||||
RLR | |||||
 | RIG-I | Virus | Absent | Present | Virus |
MDA5 | Virus | Present | Present | Virus | |
LGP2 | Virus | Present | Present | Virus | |
NLR | |||||
NOD | NOD1 | Bacteria | Present | Not reported | Unknown |
NOD2 | Bacteria | Absent | Not reported | Unknown |