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Figure 1 | Veterinary Research

Figure 1

From: Heme oxygenase-1 activity is involved in the control of Toxoplasma gondii infection in the lung of BALB/c and C57BL/6 and in the small intestine of C57BL/6 mice

Figure 1

Bilirubin serum levels (a), morbidity score (b), and body weight changes (c) of infected mice. BALB/c and C57BL/6 mice were infected with 5 T. gondii cysts and treated with the inhibitor (ZnPPIX, 10 mg/kg/day) or inducer (hemin, 5 mg/kg/day) of HO-1 activity or vehicle (Na2CO3 + NaCl). Bilirubin levels were measured in sera of infected mice by an analytic kit as an indicative of HO-1 activity. Clinical parameters were observed daily until 12 dpi. Data are representative of at least two independent experiments of at least five mice per group. *Statistically significant differences between different treatment conditions of BALB/c and C57BL/6 mice (ANOVA and Bonferroni multiple comparison post-test, P < 0.05). #Statistically significant differences between the two mouse lineages submitted to the same treatment conditions (Student’s t test, P < 0.05).

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Veterinary Research

ISSN: 1297-9716