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Table 2 Monocyte subpopulations in various body compartments from control and APP-infected pigs.

From: Distribution of porcine monocytes in different lymphoid tissues and the lungs during experimental Actinobacillus pleuropneumoniae infection and the role of chemokines

  

CD163-

CD163+

% CD163+

n

Control

APP-infected

Control

APP-infected

Control

APP-infected

Bone marrow

5

1571 ± 118

464 ± 83**

1020 ± 161

1430 ± 142

38.6 ± 2.7

75.2 ± 4.3**

Peripheral blood

5

418 ± 61

184 ± 44*

418 ± 111

1142 ± 255*

47.1 ± 6.9

86.2 ± 0.5**

Spleen

4

3009 ± 916

1052 ± 273*

3524 ± 1,043

10 886 ± 3359

54.8 ± 9.6

90.0 ± 1.8*

Lungs

Unaffected area

5

1459 ± 336

735 ± 225*

3384 ± 702

7555 ± 1493*

69.0 ± 7.4

90.9 ± 2.1**

Demarcation zone

4

 

985 ± 467

 

11 890 ± 4331

 

90.4 ± 3.8*

Necrotic area

5

 

2873 ± 1,441

 

5948 ± 2232

 

66.2 ± 6.0

Tracheobronchial LN

5

n.d.

1547 ± 674*

n.d.

16 563 ± 4284*

n.d.

92.9 ± 1.7

Mesenteric LN

4

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

  1. The data are shown as total count × 103 of monocyte subpopulations per g of tissue of per mL of PB or as a percentage of CD163+ monocytes from CD163+ and CD163- monocytes as measured by flow cytometry. Data are expressed as mean ± S.E.M. The significant differences (Mann–Whitney U test) between control and APP-infected pigs are marked with *P < 0.05, **P < 0.01. The values which were elevated between control and APP-infected pigs are highlighted in bold. LN, lymph node, n.d, non-detected.