Figure 4
PCV2a-specific humoral and cell-mediated immune responses. Log2 transformed group means for PCV2a-specific immunoperoxidase monolayer assay (IPMA) titers (A), neutralizing antibody (NA) titers (B), and frequency of PCV2a-specific interferon-γ-secreting cells (IFN- γ-SC)/106 peripheral blood mononuclear cells (PBMC) (C) from 7 different groups (commercial inactivated chimeric PCV1-2 vaccinated PCV2a-challenged PCV2b-viremic pigs (group 7), experimental inactivated PCV2 vaccinated PCV2a-challenged PCV2b-viremic pigs (group 8), commercial inactivated chimeric PCV1-2 vaccinated unchallenged PCV2b-viremic pigs (group 9), experimental inactivated PCV2 vaccinated unchallenged PCV2b-viremic pigs (group 10), unvaccinated PCV2a-challenged PCV2b-viremic pigs (group 11), unvaccinated unchallenged PCV2b-viremic pigs (group 12), and unvaccinated PCV2a-challenged non-PCV2-viremic pigs (group 13)). Different letters (a, b, c, and d) indicate statistically significant differences (P < 0.05) among groups.