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Figure 3 | Veterinary Research

Figure 3

From: Myosins 1 and 6, myosin light chain kinase, actin and microtubules cooperate during antibody-mediated internalisation and trafficking of membrane-expressed viral antigens in feline infectious peritonitis virus infected monocytes

Figure 3

The role of myosin 1 and 6 during the internalisation of viral antigens. (A) Confocal images of the internalisation process at different times post antibody addition, in which the antigen-antibody complexes was visualised with FITC (green signal). Myosins were visualised in red with Texas Red (Myo1) or Alexa Fluor 594 (myo6). (B + C) The effect of ML-7 on the recruitment of myosin 1 (B) or myosin 6 (C) in the internalisation of antigen-antibody complexes. Cells were pretreated with ML-7 for 30 min. Cells were fixed before or 30 min after antibody addition. Antigen-antibody complexes were visualised in green and myosin in red. Arrowheads indicate colocalisation of myosins with antigen-antibody complexes. All images show a single optical section through the cell. Scale bars represent 5 μm.

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Veterinary Research

ISSN: 1297-9716