Skip to main content

Table 2 The relationship between clinical signs, post-mortem lesions, recoveries of APEC strain χ 7122nal R from lung and liver and splenocyte proliferation in response to χ 7122nal R soluble antigen in the first 14 dpi

From: Analysis of immune responses induced by avian pathogenic Escherichia coli infection in turkeys and their association with resistance to homologous re-challenge

Parameter

Dpi

 

Day 1

Day 3

Day 5

Day 7

Day 14

 

Bird number

Bird number

Bird number

Bird number

Bird number

 

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

22

23

24

25

Clinical signs1

+

+

+

+

+

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

-

Post-mortem lesions2

+

+

+

+

+

+

+

+

+

+

+

+

+

-

-

+

-

-

-

-

-

-

-

-

-

Log10CFU APEC

                         

 Lung

8.9

7.6

7.2

7.5

7.6

6.1

5.2

4.2

5.1

6.8

5.3

4.2

6.4

5.4

5.3

5.2

4.2

7.0

5.8

5.6

0

0

0

0

0

 Liver

8.3

7.1

6.5

5.9

6.1

4.7

4.2

1.0*

1.0*

1.0*

4.2

1.0*

4.5

1.0*

0

3.2

3.3

1.0*

0

0

0

0

0

0

0

Splenocyte proliferation3

-

-

-

-

-

-

-

-

-

-

-

-

-

-

+ a

-

-

-

+ a

+ a

+ b

+ b

+ b

+ b

+ b

  1. 1Depression, ruffled feathers, hunched posture.
  2. 2Airsacculitis, pericarditis, perihepatitis, fibrin on serosal surfaces; + = presence any of the clinical or pathological signs; - = absence of any observable clinical or pathological signs. None of these clinical signs or post-mortem lesions was seen in the control group of birds given sterile saline.
  3. 3Splenocyte proliferation, - = no response; +a = counts between 200–250 cpm; +b = counts ≥ 2000 cpm.
  4. Bacterial recoveries from lung and liver are given as log10CFU. * = denotes a theoretical value of bacteria obtained after enrichment.