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Table 4 Differential expression of the selected gene set in abomasal mucosa (AFM) and draining lymph node (ALN)

From: Functional investigation of a QTL affecting resistance to Haemonchus contortus in sheep

Tissue

Gene

FC Ri vs Ni

FC Ri vs Ru

FC Ni vs Nu

FC Ru vs Nu

AFM

IL4

4.07*

2.22

0.54

1.16

IL13

4.51**

4.79*

1.06

0.93

IFNγ

0.83

1.13

1.36

1.47

TNFα

0.85

0.63

0.74

1.23

LGALS15

7.02

576*

82.0*

0.60

ITLN2

6.97

22.4

3.22

4.94

TFF3

1.61

6.86*

4.26

1.50

CCL26

Not tested in this tissue

TNFRSF4

Not tested in this tissue

CXCL14

Not tested in this tissue

PAPPA2

1.18

0.34

0.29*

1.08

ALN

IL4

1.22

2.33*

1.91

0.81

IL13

1.24

0.50

0.41

0.78

IFNγ

0.69

0.33**

0.48

1.08

TNFα

0.70*

0.62

0.88

1.12

LGALS15

Not tested in this tissue

ITLN2

Not tested in this tissue

TFF3

Not tested in this tissue

CCL26

1.65

1.13

0.69

0.87

TNFRSF4

0.68

0.59

0.87

1.11

CXCL14

1.45

1.56

1.08

0.44

PAPPA2

1.06

0.52

0.49*

0.88

  1. Fold changes (FC) between the four considered groups (resistant allele carriers infected and uninfected (Ri and Ru respectively) and susceptible allele carriers infected and uninfected (Ni and Nu respectively) are provided. Significant differences (nominal p-value < 0.01) are indicated with **, and suggestive differences (nominal p-value < 0.05) are marked as *.