VIRUS STRAIN | Time of AIV NP antigen detection | Main localization | |||
---|---|---|---|---|---|
Tissue | 1 dpi | 2 dpi | 3 dpi | 4 dpi | |
FPV | |||||
CNS | - | - | + | + | Neurons, glial cells |
Heart | - | + | + | + | Myocytes |
Kidney | - | - | −/+ | + | Epithelialtubularcells |
Pancreas | - | - | + | + | Exocrine acinar cells |
Liver | - | - | + | + | Kupffer’s cells |
Spleen | - | - | + | + | Macrophages |
Thymus | - | + | + | + | Macrophages |
Bursa of Fabricius | - | - | + | + | Macrophages |
FPV NS GD | |||||
CNS | - | - | ++ | + | Neurons, glial cells, ependymalcells |
Heart | - | ++ | + | + | Myocytes, macrophages |
Kidney | - | +++ | ++ | ++ | Epithelial tubular cells |
Pancreas | - | - | ++ | + | Exocrine acinar cells |
Liver | - | - | + | + | Kupffer’s cells |
Spleen | - | + | + | + | Macrophages, Endothelial cells |
Thymus | - | + | + | + | Macrophages, Endothelial cells |
Bursa of Fabricius | - | - | + | + | Macrophages, Endothelial cells |
FPV NS VN | |||||
CNS | - | - | ++ | + | Neurons, glial cells, ependymalcells |
Heart | - | ++ | + | + | Myocytes, macrophages |
Kidney | - | - | ++ | ++ | Epithelial tubular cells |
Pancreas | - | - | ++ | + | Exocrine acinar cells |
Liver | - | - | + | + | Kupffer’s cells |
Spleen | - | - | + | + | Macrophages, Endothelial cells |
Thymus | - | - | + | + | Macrophages, Endothelial cells |
Bursa of Fabricius | - | - | + | + | Macrophages, Endothelial cells |
Saline Solution | |||||
CNS | - | - | - | - | - |
Heart | - | - | - | - | - |
Kidney | - | - | - | - | - |
Pancreas | - | - | - | - | - |
Liver | - | - | - | - | - |
Spleen | - | - | - | - | - |
Thymus | - | - | - | - | - |
Bursa of Fabricius | - | - | - | - | - |