Figure 3From: Topology and biological function of enterovirus non-structural protein 2B as a member of the viroporin familySketch map of apoptosis and autophagy induced by protein 2B. The 2B protein can embed into the cytomembrane, ER, and mitochondrial membrane to increase cell permeability, disturb intracellular Ca2+ equilibrium, and ultimately induce apoptosis and autophagy of host cells. Adapted from [26] and [34].Back to article page