Figure 1From: Immunity, safety and protection of an Adenovirus 5 prime - Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calvesWhole blood PPD-J stimulated IFN-? release assay. IFN-? release from A. PPD-J, B. PPD-A, C. PPD-B stimulated whole blood taken from HAV vaccinated (black triangles) and Sham vaccinated (grey squares) calves including samples taken week -11, immediately prior prime vaccination; week -5, immediately prior boost vaccination; week 0, immediately prior to MAP challenge and up to 33Â weeks post challenge. OD values are adjusted to internal controls to remove assay variation between runs. Significance indicated as *P < 0.05, **P < 0.01.Back to article page