3 h E. coli- challenged vs. unchallenged control cells | p -value of overlap |
---|---|
IL1B (proinflammatory; proliferation; differentiation; apoptosis) | 6.80E-23 |
lipopolysaccharide (increase of TLR4 expression; innate immune response) | 8.75E-22 |
IRAK4 (activation of NF-kB; innate immune response) | 6.93E-21 |
TNF (proinflammat.; proliferation; differentiation; apoptosis; lipid metabolism; coagulation) | 1.17E-20 |
cycloheximide (inhibitor of protein synthesis; apoptosis, cell death) | 3.04E-20 |
3 h S. aureus- challenged vs. unchallenged control cells | p -value of overlap |
beta-estradiol (proliferation; growth; apoptosis; breast cancer signaling) | 1.20E-10 |
ESR1 (growth; proliferation; transcription; transactivation) | 2.00E-09 |
U0126 (inhibitor of MAP kinase kinase; apoptosis; proliferation; migration) | 3.74E-09 |
3-methylcholanthrene (carcinogen; transformation; proliferation) | 1.59E-08 |
paclitaxel (antimitotic; apoptosis; growth; survival; cell viability) | 2.55E-08 |
24 h E. coli- challenged vs. unchallenged control cells | p -value of overlap |
PD98059 (inhibitor of MAP kinase kinase; apoptosis; proliferation; migration) | 1.98E-11 |
IKBKB (activation of NF-kB; apoptosis; proliferation) | 8.45E-11 |
TGFB1 (proliferation; differentiation; adhesion; migration; apoptosis; growth) | 1.47E-10 |
RAF1 (activation of MEK1/2; apoptosis; proliferation; differentiation; cell cycle; migration) | 1.90E-10 |
HGF (activation of tyrosine kinases; migration; proliferation; scattering; apoptosis; growth) | 9.20E-10 |
24 h S. aureus- challenged vs. unchallenged control cells | p -value of overlap |
RAF1 (activation of MEK1/2; apoptosis; proliferation; differentiation; cell cycle; migration) | 2.30E-09 |
E2F1 (apoptosis; proliferation; cell cycle) | 3.32E-08 |
TP53 (tumor suppressor; apoptosis; cell cycle; growth; proliferation) | 3.45E-07 |
INSR (proliferation; growth; differentiation; migration; mitogenesis) | 9.61E-07 |
PD98059 (inhibitor of MAP kinase kinase; apoptosis; proliferation; migration) | 1.24E-06 |