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Table 2 Results of the pathogenicity and by contact transmission experiment

From: Susceptibility to and transmission of H5N1 and H7N1 highly pathogenic avian influenza viruses in bank voles (Myodes glareolus)

Virus Sample Day pi/pc Infected Sentinels
RRT-PCR Ct ± SD VI RRT-PCR Ct VI
Os/H7N1 Lungs 3 +2/2 26.22 ± 1.1 +2/2 - - nt
4 +2/2 22.33 ± 0.08 +2/2 +1/2 28.24 +1/1
Nasal wash 3 +1/2 32.13 - - - nt
4 +1/2 30.57 - +1/2 35 -
Brain 3 +1/2 30.01 - - - nt
4 - - nt - - nt
Spleen 3 +2/2 28 ± 3.5 +1/2 - - nt
4 - - nt - - nt
Kidney 3 +1/2 29.6 - - - nt
Tk/H5N1 Lungs 2a +1/1 20.22 +1/1 nt nt nt
3 +2/2 22.19 ± 2 +2/2 - - nt
4 +2/2 27.3 ± 3.4 +2/2 +1/2 24.03 +1/1
Nasal wash 2a +1/1 26.95 - nt nt nt
3 +2/2 29 ± 2.1 +2/2 - - nt
4 +2/2 34.7 ± 0.1 - - - nt
Brain 2a - - nt nt nt nt
3 - - nt - - nt
4 +1/2 33.48 - - - nt
Spleen 2a +1/1 33.12 - nt nt nt
3 - - nt - - nt
4 - - nt - - nt
  1. pi: post-infection; pc: post-contact; Ct: quantification cycle; SD: standard deviation; VI: virus isolation; adead vole with clinical signs on day 2 pi; −: all samples tested negative; nt: not tested.
  2. RRT-PCR (mean of Ct values ± SD) and virus isolation results of the different organs and nasal washes collected from infected voles and in contact sentinels on days 3 and 4 pi/pc.