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Table 3 Summary of the main results obtained in contact partridges

From: Bagaza virus is pathogenic and transmitted by direct contact in experimentally infected partridges, but is not infectious in house sparrows and adult mice

 

Contact 1

Contact 2

Contact 3

Contact 4

dpi

7

9

11

15

18

7

9

11

15

18

7

9

11

15

18

7

9

11

15

18

% init. weight

96

94

91

81

83

98

97

98

100

96

98

97

97

91

76

99

99

100

90

91

VNT titre

<10

<10

20

640

320

<10

<10

<10

<10

<10

<10

<10

<10

80

320

<10

<10

<10

160

320

VL blood (Ct)

29

30

32

39

38

>40

>40

>40

26

29

>40

>40

25

33

38

>40

25

20

33

35

VL oral. (Ct)

37

28

24

29

>40

>40

>40

>40

>40

25

33

>40

33

28

31

>40

33

28

28

36

VL cloacal (Ct)

>40

>40

>40

>40

>40

>40

>40

>40

>40

28

>40

>40

>40

37

>40

>40

>40

37

>40

36

VL feather (Ct)

34

20

20

24

37

>40

>40

>40

25

20

>40

>40

23

21

23

>40

35

19

22

24

 

Contact 1

Contact 2

Contact 3

Contact 4

VL in organs (18 dpi)

brain

heart

kidney

spleen

liver

brain

heart

kidney

spleen

liver

brain

heart

kidney

spleen

liver

brain

heart

kidney

spleen

liver

32

33

32

34

36

19

19

20

25

21

23

32

25

22

33

28

26

26

29

32

  1. The upper part of the table shows the values obtained from the four contact partridges on different days post-inoculation (dpi) for the following parameters: percentage of weight compared to initial weight at day 0 (% init. weight); neutralizing antibody titre in serum measured by the virus neutralization test (VNT titre); viral load (VL) in blood, oral and cloacal swabs and in feathers, as measured by real time RT-PCR, expressed in Ct values. The bottom part of the table shows the observed viral load (VL) measured by real-time RT-PCR (expressed in Ct values) in five different organs (the brain, heart, kidney, spleen and liver) at the time of necropsy of the contact partridges (18 dpi) (neg = Ct ≥40).