Figure 3From: Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses DUB activity of L pro in innate immune signaling pathways. Lpro can deubiquitinate several adaptor proteins including RIG-I, TRAF3, TRAF6, and TBK1. Deubiquitination of these proteins contributes to the attenuation of host innate immune responses.Back to article page