From: Transmission of sheep-bovine spongiform encephalopathy to pigs
SITE | Tissue | P1 | P2 | P3 | P4 | P5 | P6 | P8 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IHC | EIA | IHC | EIA | IHC | EIA | IHC | EIA | IHC | EIA | IHC | EIA | IHC | EIA | ||
CNS | Brain | + | 4.22 | + | 3.93 | + | 3.69 | + | 3.75 | + | 3.90 | + | 4.34 | – | 0.03 |
Retina | + | ND | + | ND | + | ND | + | ND | + | ND | + | ND | – | ND | |
Optic nerve | + | ND | + | ND | + | ND | + | ND | + | ND | + | ND | – | ND | |
PNS | Vagus nerve | + | ND | + | ND | + | ND | + | ND | + | ND | + | ND | – | – |
Brachial nerve | – | – | + | 0.20 | + | 0.17 | – | – | – | – | – | – | – | – | |
Sciatic nerve | + | 0.43 | + | 0.30 | + | 0.28 | + | 0.29 | + | 0.34 | + | 0.16 | – | – | |
LRS | Tonsil | + | 0.17 | + | 0.08 | – | – | + | 0.15 | – | – | – | – | – | – |
Retropharyngeal ln. | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Submandibular ln. | – | – | – | 0.35 | – | – | – | – | – | – | – | – | – | – | |
Prescapular ln. | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Mediastinal ln. | + | 0.16 | – | – | – | – | – | – | – | – | – | – | – | – | |
Spleen | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Mesenterial ln. | – | – | + | 0.23 | – | – | + | 0.19 | + | 0.54 | – | – | – | – | |
Popliteal ln. | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
GIT | Oesophagus | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Stomach | + | – | – | – | – | – | – | – | – | – | + | – | – | – | |
Duodenum | ++ | – | – | – | – | – | ++ | – | – | – | + | – | – | – | |
Jejunum | ++ | 0.24 | – | – | + | – | ++ | – | – | – | + | – | – | – | |
Ileum | +++ | 0.40 | +++ | 0.72 | ++ | 0.22 | +++ | 1.48 | + | 0.23 | ++ | 0.31 | – | – | |
Caecum | + | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Colon | + | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Rectum | + | – | – | – | – | – | – | – | – | – | – | – | – | – | |
SM | Oculomotor | + | 1.00 | – | – | – | – | + | 2.83 | – | 0.67 | – | – | – | – |
Brachial biceps | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Semitendinosus | – | – | – | – | – | – | – | – | – | 0.20 | – | – | – | – | |
Other | Tongue | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Olfactory mucosa | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Heart | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Lung | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Liver | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Adrenal gland | – | – | – | – | + | 0.15 | – | – | + | 0.19 | – | – | – | – | |
Urinary bladder | – | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Kidney | + | – | – | – | – | – | – | – | – | – | – | – | – | – | |
Pancreas | + | – | – | – | + | – | + | 0.21 | + | – | + | – | – | – | |
Uterus | – | – | – | – | – | – | – | – | – | – | – | – | – | – |