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Table 2 Clusters of Biological Process GO terms over-represented in the common response gene list

From: Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells

Biological process GO terms

Genes

Regulation of cell communication

e.g., positive regulation of cell communication

positive regulation of signal transduction

positive regulation of protein kinase cascade

positive regulation of I-κB/NF-κB cascade

BST2, CD80, CFLAR, CSF2, EDN1, F3, IL6, PLK2, PTGS2, REL, TNF, TNFAIP3, VEGFA

Regulation of programmed cell death

e.g., regulation of programmed cell death

regulation of apoptosis

negative regulation of programmed cell death

anti-apoptosis

BCL2A1, BTG2, CFLAR, CSF2, F3, GADD45B, IER3, IL6, NR4A1, PMAIP1, PTGS2, RYBP, TNF, TNFAIP3, TRAF1, VEGFA

Immune response

e.g., inflammatory response

immune response

response to bacterium

chemotaxis

BST2, CCL5, CCL20, CSF2, CXCL2, EDN1, F3, IL6, KDM6B, MEFV, NOS2, PTGS2, RNF19B, TNF, VEGFA

  1. Differentially expressed genes (FDR < 0.05, fold change >1.8) identified as common response genes. Genes are listed by HUGO gene symbol and were identified from functional analysis using human gene annotation data. Those indicated in italics were also identified from analysis using bovine gene annotation data.