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Table 2 Clinical outcome of the immunized pigs following virulent challenge

From: Enhanced protective immunity of the chimeric vector-based vaccine rAdV-SFV-E2 against classical swine fever in pigs by a Salmonella bacterial ghost adjuvant

Groups

Days to fever onset

Fever ratea

Fever frequencyb

Survival rate

A: rAdV-SFV-E2 (106 TCID50)

0/4

0/60

4/4

B: rAdV-SFV-E2 (105 TCID50) + BG (1010 CFU)

0/4

0/60

4/4

C: rAdV-SFV-E2 (105 TCID50)

3

3/4

14/50

3/4

D: BG (1010 CFU)

3

4/4

27/46

0/4

E: DMEM

3

4/4

27/44

0/4

  1. Five groups of pigs (n = 4) were immunized and challenged as described in the “Materials and methods” section. Following challenge, the clinical signs and rectal temperatures were recorded daily. Fever is defined as rectal temperature ≥40.5 °C.
  2. no fever, CFU: colony forming units.
  3. aNumbers of pigs showing fever/total numbers of pigs in each group.
  4. bTotal days with any pig showing fever/total days of monitored for all the pigs in a group following virulent challenge.