Figure 2
From: Immunomodulation in the canine endometrium by uteropathogenic Escherichia coli
Transcription of TLRs signaling components in diestrous and pyometra endometria. A Representative PCR detection of transcripts of TLRs signaling components and of cytokines in diestrous and pyometra endometria. NC negative control. B Relative mRNA expression level (arbitrary units, AU) of IL-1β, IL-6, IL-8, IL-10, and TGFβ evaluated by real-time PCR, in hemolytic E. coli endometria, non-hemolytic E. coli endometria and diestrous endometria. Data are given as mean ± SEM. Columns with different superscripts differ significantly (IL-1β, IL-6, IL-8 a vs b p < 0.01a,b vs c; p < 0.00001; IL-10, TGFβ a vs b p < 0.0001). MyD88 (myeloid differentiation factor 88); TRAM (TRIF related adaptor molecule); TRAF6 (TNFR-associated factor 6); TRIF (TIR domain-containing adaptor inducing interferon (IFN)-β); IRF3 (interferon regulatory factor 3).