Table 3 Clinical score and post-mortem findings recorded for the SPF pigs in the natural challenge experiment
From: Innate immune responses induced by the saponin adjuvant Matrix-M in specific pathogen free pigs
Pig ID | Clinical findings | Post-mortem examination | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
General condition | Respiratory signs | Other | DLN | Lung | BLN | Joints | Other | |||
Scorea | Onsetb (day) | Scorea | Onsetb (day) | |||||||
SPFMatrix-M/SPF | ||||||||||
#1 | – | – | – | – | Lamenessc | – | – | – | – | Abscessd |
#2 | – | – | – | – | – | – | – | – | – | – |
#3 | – | – | – | – | – | 2 | – | – | – | – |
#4 | – | – | – | – | – | – | – | – | – | – |
SPFSaline/SPF | ||||||||||
#5 | – | – | – | – | – | – | – | – | – | – |
#6 | – | – | – | – | – | – | – | – | – | – |
#7 | – | – | – | – | – | – | – | – | – | – |
#8 | – | – | – | – | – | – | – | – | – | – |
SPFMatrix-M/Conv | ||||||||||
#9 | – | – | 0.5 | 1 | – | – | 0.5 | 1 | – | – |
#10 | – | – | 0.5 | 1 | – | 1 | – | 1 | – | – |
#11 | – | – | 0.5 | 2 | – | 1 | 0.5 | – | – | – |
#12 | – | – | 1 | 3 | – | 1 | 0.5 | – | – | – |
SPFSaline/Conv | ||||||||||
#13 | – | – | 0.5 | 1 | – | – | 0.5 | 0.5 | – | – |
#14 | 2 | 3 | 1 | 1 | Lamenesse | – | 3 | 1 | 3 | Ascitesf |
#15 | – | – | 1 | 2 | – | – | – | 1 | – | – |
#16 | 1 | 2 | 1 | 1 | Lamenessc | – | – | – | 2 | – |