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Table 2 Comparison of the duration of pre-breeding to post-breeding antibody responses to C. burnetii in goats.

From: A longitudinal study of serological responses to Coxiella burnetii and shedding at kidding among intensively-managed goats supports early use of vaccines

Antibody type

Type of immune response

Time of occurrence

Duration of antibody responses in weeks

n (rev)

Mean

Median (range)

p value*

IgM phase 2

Primary

Pre-breeding

57 (55)

10.9

5.5 (1.0, 51.0)

0.570

Post-breeding

7 (7)

5.9

6.0 (2.0, 12.0)

 

Secondary

Pre-breeding

24 (24)

10.4

9.0 (1.0, 34.0)

0.523

Post-breeding

18 (18)

8.4

4.0 (2.0, 33.0)

 

IgG phase 2

Primary

Pre-breeding

40 (27)

19.4

12.0 (1.0, 48.5)

0.376

Post-breeding

14 (5)

7.5

6.0 (2.5, 13.0)

 

Secondary

Pre-breeding

4 (3)

30.7

42.5 (3.0, 46.5)

0.564

Post-breeding

7 (2)

25.8

25.8 (17.0, 34.5)

 

IgM phase 1

Primary

Pre-breeding

29 (29)

5.1

4.0 (1.0, 12.0)

0.197

Post-breeding

9 (7)

2.9

3.0 (1.0, 6.0)

 

Secondary

Pre-breeding

3 (3)

1.3

1.0 (1.0, 2.0)

0.127

Post-breeding

4 (4)

2.9

3.5 (1.0, 3.5)

 

IgG phase 1

Primary

Pre-breeding

40 (12)

23.7

22.5 (5.0, 42.5)

0.897

Post-breeding

14 (14)

20.5

22.3 (5.0, 34.5)

 

Secondary

Pre-breeding

0 (0)

–

–

–

Post-breeding

1 (1)

11.5

–

 
  1. Pre-breeding responses are those that started before the target breeding age while post-breeding responses are those that started after the target breeding age in intensively managed goats on the study farm in Victoria, Australia, 2014–2015
  2. rev. number of antibody responses that seroreverted (moved from positive to negative) which were used in calculating the duration of serological positivity, n total number of antibody responses
  3. * p values derived using the Mann–Whitney U test comparing the duration of pre-breeding immune responses to the post-breeding immune responses