Basis of diagnosis | Tissuea | Fluid | Faeces | |
---|---|---|---|---|
Sensitivity % (n = positive/total) | RT-qPCR alone | 89.8 (n = 202/225) | 78.4 (n = 40/51) | 64.6 (n = 31/48) |
Combination testingb | 80.9 (n = 182/225) | 60 (n = 30/50)c | 33.3 (n = 16/48) | |
Specificity % (n = negative/total) | RT-qPCR alone | 92.6 (n = 239/258) | 97.9 (n = 46/47) | 80 (n = 28/35) |
Combination testingb | 94.6 (n = 244/258) | 97.9 (n = 46/47) | 100 (n = 35/35) | |
Accuracy % (n = true result/total) | RT-qPCR alone | 91.3 (n = 441/483) | 87.8 (n = 86/98) | 71.1 (n = 59/83) |
Combination testingb | 88.2 (n = 426/483) | 78.4 (n = 76/97) | 61.4 (n = 41/83) |