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Figure 8 | Veterinary Research

Figure 8

From: Salmonella enterica serovar Choleraesuis vector delivering SaoA antigen confers protection against Streptococcus suis serotypes 2 and 7 in mice and pigs

Figure 8

Protection in pigs. A Survival curve of swine after challenge with SS2. Groups of ten pigs were orally immunized twice at 3-week intervals with indicated strains and challenged intravenously with 108 CFU of S. suis 2 at 2 weeks after the 2nd immunization. (B) Clinical symptom of leg and histopathology in the brain of immunized pigs challenged with SS2. (C) Western blots analysis the ability of sera from the pigs vaccinated with rSC0016 or rSC0018 containing pS-SaoA plasmid to recognize SaoA protein of SS2 and SS7. PB: Post-boost serum of pigs. (D) Rectal temperature of immunized piglets after challenged intravenously with 1010 CFU of SS7. The rectal temperatures were measured at 0, 1, 2, 3, 4, 5, 6, and 7 days after challenge. The experiment was performed twice.

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