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Table 2 Virus replication of Δ003, Δ010, ΔTK, and wtSPV in different cell lines (log PFU/mL)

From: Swinepox virus vector-based vaccines: attenuation and biosafety assessments following subcutaneous prick inoculation

 

Cell line

N1

N2

N3

N4

N5

N6

N7

N8

N9

N10

Δ003

PK-15

2.8

2.9

3.0

2.9

3.0

3.1

2.9

3.0

2.9

2.9

Vero

3.2

3.2

3.0

3.2

3.2

3.2

3.2

3.0

3.2

3.2

DF-1

2.7

1.7

1.5

ND

ND

ND

ND

ND

ND

ND

LLC

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

BHK

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDCK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDBK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

F81

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

RK13

2.7

2.0

2.0

ND

ND

ND

ND

ND

ND

ND

HELA

2.7

2.0

2.0

ND

ND

ND

ND

ND

ND

ND

Δ010

PK-15

5.0

4.9

4.8

4.9

5.0

5.0

5.0

4.8

4.8

4.9

Vero

5.2

5.2

5.0

5.2

5.2

5.0

5.1

5.2

5.2

5.2

DF-1

3.5

2.6

1.7

ND

ND

ND

ND

ND

ND

ND

LLC

1.4

ND

ND

ND

ND

ND

ND

ND

ND

ND

BHK

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDCK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDBK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

F81

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

RK13

3.7

3.0

2.0

ND

ND

ND

ND

ND

ND

ND

HELA

4.7

3.8

2.0

ND

ND

ND

ND

ND

ND

ND

ΔTK

PK-15

2.8

2.9

2.8

2.8

2.8

2.8

2.8

2.8

2.8

2.8

Vero

3.1

3.2

3.0

3.2

3.2

3.0

3.0

3.0

3.0

3.0

DF-1

2.7

1.7

1.2

ND

ND

ND

ND

ND

ND

ND

LLC

1.4

ND

ND

ND

ND

ND

ND

ND

ND

ND

BHK

1.1

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDCK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDBK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

F81

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

RK13

2.6

2.2

1.8

ND

ND

ND

ND

ND

ND

ND

HELA

2.8

2.0

1.6

ND

ND

ND

ND

ND

ND

ND

wtSPV

PK-15

6.1

5.9

6.0

6.2

6.0

5.9

5.9

6.0

6.0

6.1

Vero

5.2

5.2

5.0

5.2

5.2

5.2

5.0

5.2

5.2

5.2

DF-1

3.7

2.8

1.8

ND

ND

ND

ND

ND

ND

ND

LLC

1.4

ND

ND

ND

ND

ND

ND

ND

ND

ND

BHK

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDCK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

MDBK

1.0

ND

ND

ND

ND

ND

ND

ND

ND

ND

F81

1.2

ND

ND

ND

ND

ND

ND

ND

ND

ND

RK13

3.7

2.5

2.0

ND

ND

ND

ND

ND

ND

ND

HELA

4.7

3.0

2.2

ND

ND

ND

ND

ND

ND

ND

  1. ND: not detected.