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Table 1 Infectivity, lethality, and transmission study design and summary results

From: Pathobiology of Tennessee 2017 H7N9 low and high pathogenicity avian influenza viruses in commercial broiler breeders and specific pathogen free layer chickens

Bird type (age)

Challenge virus

Dose (log10)

Inoculated infected/totala

BID50 (log10)

Inoculated dead/total (MDTb)

BLD50 (log10)

Contact-exposed infected/totalc

Broiler breeders (36w)

H7N9 LPAI

2

0/5

5.6

0/5

>6

nd

 

4

2/5

 

0/5

 

nd

 

6

2/5

 

0/5

 

nd

–

sham

0/5

–

0/5

–

–

SPF White Leghorn (4w)

H7N9 LPAI

2

0/5

4.3

0/5

>6

0/3

 

4

2/5

 

0/5

 

0/3

 

6

5/5

 

0/5

 

0/3

SPF White Leghorn (4w)

H7N9 HPAI

2

3/5

<2

3/5 (2.3)

<2

0/3

 

4

5/5

 

5/5 (≤2.4)

 

0/3

 

6

5/5

 

5/5 (2.2)

 

1/3 (dead)

–

sham

0/5

–

0/5

–

–

  1. BID50: mean bird infectious dose, BLD50: mean bird lethal dose, MDT: mean death time in days, nd: not determined.
  2. aBirds were considered infected if they shed virus and/or were positive for antibodies at 14 dpc.
  3. b#dead birds × dpc/total dead birds.
  4. cContact-exposed birds were considered infected if they died, shed virus, and/or were positive for antibodies at 14 dpc.
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