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Table 4 The top proteins with the largest change in expression in response to ASFV infection (7 dpi)

From: Comparative proteomic analysis reveals different responses in porcine lymph nodes to virulent and attenuated homologous African swine fever virus strains

 

Attenuated-control

ID SSP

ID

Gen name

Protein name

pI

Mw (kDa)

% coverage

Fold change

p value

1509

Q0QEM6

ATP5B

ATP synthase subunit beta Sus scrofa

4.99

47.10

72

26.6

0.0236

1405

F8VYX6

TUBB

Tubulin beta chain Homo sapiens

5.1

48.90

37

9.1

0.0222

8512

F1RFI1

TUFM

Elongation factor Tu Sus scrofa

6.72

49.70

46

6

0.0004

8606

P01790

IGH

Ig heavy chain V region Mus musculus

8.01

13.70

24

5.7

0.0232

1612

P02543

VIM

Vimentin Sus scrofa

5.06

53.70

57

4.5

0.0097

3319

B4DWA6

CAPZB

Highly similar to F-actin capping protein subunit beta Homo sapiens

5.77

37.8

31

4.1

0

4005

Q2TBX5

SSR4

Translocon-associated protein subunit delta Bos taurus

5.49

19.00

37

3.9

0.095

7412

Q9GKX6

GALM

Aldose 1-epimerase Sus scrofa

6.31

38.00

30

3.7

0.0044

8209

B5APU7

ARPC2

Actin-related protein 2/3 complex subunit 2 Sus scrofa

6.84

34.3

63

3.7

0.025

7108

D6RBM0

HNRNPH1

Heterogeneous nuclear ribonucleoprotein H Homo sapiens

6.97

24.2

62

3.7

0.0033

3005

B3KWQ3

ACTG

Highly similar to Actin. cytoplasmic 2 Homo sapiens

5.2

28.50

29

− 12

0.0055

7309

F1RUN2

ALB

Serum albumin Sus scrofa

5.98

71.60

30

− 5

0.0004

3720

Q5T6W5

HNRNPK

Heterogeneous nuclear ribonucleoprotein K Homo sapiens

5.46

47.70

41

− 4.9

0.018

1308

A5D989

EEF1D

Elongation factor 1-delta Bos taurus

4.94

31.2

27

− 4.8

0

3723

F1MUZ9

HSPD1

60 kDa chaperonin Bos taurus

5.71

61.10

42

− 4.3

0.0017

3318

P11493|

PPP2CB

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Homo sapiens

5.46

34.1

35

− 3.2

0.023

4112

Q1W2K3

PSMB10

Proteasome subunit beta Sus scrofa

6.09

29.20

23

− 3.2

0.0004

2613

F1RG16

HNRNPF

Heterogeneous nuclear ribonucleoprotein F Sus scrofa

5.32

45.90

42

− 3.1

0.0452

305

I3L813

PCNA

Proliferating cell nuclear antigen Sus scrofa

4.57

29.1

63

− 2.9

0.005

2309

G7P8A3

EGM_15385

Serine/threonine-protein phosphatase Macaca fascicularis

5.55

33.9

46

− 2.4

0.0003

 

Virulent-control

ID SSP

ID

Gen name

Protein name

pI

Mw (Kda)

% coverage

Fold change

p value

3516

F1MRD0

ACTB

Actin.cytoplasmic 1.Bos taurus

5.16

42.20

38

6.1

0.0255

7309

F1RUN2

ALB

Serumalbumin Sus scrofa

5.98

71.60

30

− 26

0.011

3005

B3KWQ3

ACTG

Highly similar to Actin. cytoplasmic 2 Homo sapiens

5.2

28.50

29

− 24

0.0214

6417

Q8IY98

ACTR2

Actin-related protein 2 Homo sapiens

5.77

39.90

43

− 6.4

0.0004

6313

O88550

CASP7

Caspase 7 Rattus norvegicus

5.53

34.9

17

− 5.5

0.0125

2012

Q0IIA3

SRI

Sorcin Bos taurus

5.11

20.60

20

− 4.7

0.014

9012

Q9BGI4

PRDX1

Peroxiredoxin 1 Bos taurus

8.81

22.4

40

− 4.6

0.0013

3314

Q15181

PPA1

Inorganic pyrophosphatase Homo sapiens

5.54

33.1

41

− 4.4

0.0374

2613

F1RG16

HNRNPF

Heterogeneous nuclear ribonucleoprotein F Sus scrofa

5.32

45.90

42

− 4.3

0.0357

207

P61981

YWHAG

14-3-3 protein gamma Homo sapiens

4.8

28.4

59

− 3.4

0.017

2309

G7P8A3

EGM_15385

Serine/threonine-protein phosphatase Macaca fascicularis

5.55

33.9

46

− 2.8

0.0223

6416

Q99LC3

NDUFA10

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10. Mus musculus

7.63

40.80

22

− 2.3

0.027

2208

F2Z5C1

ANXA5

Annexin Sus scrofa

4.95

33.2

59

− 2.1

0.0313

305

I3L813

PCNA

Proliferating cell nuclear antigen Sus scrofa

4.57

29.1

63

− 2

0.0401

2108

F1SQW8

ARHGDIB

Rho protein dissociation inhibitor homolog Sus scrofa

5.08

22.90

55

− 1.8

0.047

306

F1M0S3

TPM2

Tropomyosin beta chain Rattus norvegicus

5.19

31.1

40

− 1.8

0.0155

7213

K7D9V9

HNRNPH3

Heteroproteinous nuclear ribonucleoprotein H3 Pan troglodytes

6.36

35.2

68

− 1.7

0.0419