Table 2 Summary of clinical signs and incidence of fecal virus shedding in colostrum-deprived neonatal piglets immunized with each live attenuated monovalent or trivalent vaccines and then challenged with each corresponding original virulent strain(s) (174-1, PRG942, or K71 strains)
Vaccine strain | Piglet no. | Vaccination (administrated at 3-day-old) | Challenge (inoculated at 14Â days post-vaccination) | ||
|---|---|---|---|---|---|
Occurrence of diarrhea | RT-PCR onset (duration) | Occurrence of diarrhea | RT-PCR onset (duration) | ||
174-1V-80 (G8P[7]) | 1 | None | 1 (5) | None | 14 (2) |
2 | None | 1 (4) | None | 14 (3) | |
3 | None | 1 (5) | None | 14 (3) | |
4 | None | 1 (5) | None | 14 (5) | |
5 | None | 1 (6) | None | 14 (3) | |
PRG942V-80 (G9P[23]) | 6 | None | 1 (6) | None | 14 (3) |
7 | None | 1 (5) | None | 14 (3) | |
8 | None | 1 (5) | None | 14 (4) | |
9 | None | 1 (7) | None | 14 (5) | |
10 | None | 1 (5) | None | 14 (5) | |
K71V-80 (G5P[7]) | 11 | None | 1 (7) | None | 14 (5) |
12 | None | 1 (5) | None | 14 (3) | |
13 | None | 1 (5) | None | 14 (3) | |
14 | None | 1 (3) | None | 14 (4) | |
15 | None | 1 (5) | None | 14 (5) | |
Trivalent vaccine (174-1V-80, PRG942V-80, and K71V-80) | 16 | None | 1 (5) | None | 14 (5) |
17 | None | 1 (6) | None | 14 (5) | |
18 | None | 1 (5) | None | 14 (7) | |
19 | None | 1 (7) | None | 14 (5) | |
20 | None | 1 (7) | None | 14 (5) | |
Mock-control | 21 | None | None | None | None |
22 | None | None | None | None | |
23 | None | None | None | None | |
24 | None | None | None | None | |
25 | None | None | None | None | |