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Figure 4 | Veterinary Research

Figure 4

From: Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine

Figure 4

Innocuousness of recombinant PRV GX-ΔTK/IES virus in piglets. A Time course of the body temperature in the piglets after inoculation. Values represent the mean and standard deviation of the rectal temperature of the piglets in each of the groups, including those subjected to a single dose (a, 106 TCID50), two doses (b, 106 TCID50) and a tenfold dose (c, 107 TCID50), and of PRV GX-ΔTK/IES and d (PBS)-vaccinated controls. B PRV gB-specific ELISA antibodies after immunization with PRV GX-ΔTK/IES. C PRV gE-specific ELISA antibodies after immunization with PRV GX-ΔTK/IES. The levels of specific antibody to PRV-gB and gE were detected using blocking ELISA test kits. ELISA values are given as the S/N ratio. The dotted line indicates a positive antibody response (S/N ratio > 0.6), samples with S/N ratios less than 0.6 were scored as positive, and samples with ratios between 0.6 and 0.7 were scored as suspicious. Standard deviations are shown as error bars.

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