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Table 3 Viral detection in nasal swab samples obtained from piglets inoculated with PRV GX-ΔTK/IES

From: Comprehensive evaluation of the safety and immunogenicity of a gene-deleted variant pseudorabies virus attenuated vaccine

Group

Piglet

Days post-inoculation

1

2

3

4

5

6

7

8

9

10

11

12

13

14

a (106 TCID50)

19

–a

–

–

–

–

–

–

–

–

–

–

–

–

–

20

–

–

–

–

–

–

–

/c

/

/

/

/

/

/

21

–

–

–

–

–

–

–

–

–

–

–

–

–

–

24

–

–

–

–

–

–

–

–

–

–

–

–

–

–

25

–

–

–

–

–

–

–

–

–

–

–

–

–

–

26

–

–

 + b

–

–

–

–

–

–

–

–

–

–

–

b (106 TCID50)

27

–

–

–

–

–

–

–

/

/

/

/

/

/

/

29

–

–

–

/

/

/

/

/

/

/

/

/

/

/

30

–

–

–

–

–

–

–

–

–

–

–

–

–

–

31

–

–

–

–

–

–

–

–

–

–

–

–

–

–

32

–

–

–

–

–

–

–

–

–

–

–

–

–

–

33

–

–

 + 

–

–

–

–

–

–

–

–

–

–

–

c (107 TCID50)

11

–

–

–

–

–

–

–

–

–

–

–

–

–

–

12

–

–

–

/

/

/

/

/

/

/

/

/

/

/

13

–

–

–

–

–

–

–

/

/

/

/

/

/

/

15

–

–

 + 

–

–

–

–

/

/

/

/

/

/

/

16

–

–

–

–

–

–

–

–

–

–

–

–

–

–

18

–

–

 + 

–

–

–

–

–

–

–

–

–

–

–

d (PBS)

14

–

–

–

–

–

–

–

–

–

–

–

–

–

–

22

–

–

–

–

–

–

–

–

–

–

–

–

–

–

28

–

–

–

–

–

–

–

–

–

–

–

–

–

–

  1. Animals #29 and #12 were euthanized at 3 days post-inoculation, #20, #27, #13 and #15 were euthanized at 7 days post-inoculation.
  2. aNegative sample during viral detection.
  3. bPositive sample during viral detection.
  4. cAnimals were euthanized.