Figure 3

Deduced amino acid alignment of the BVDV E2 coding region. The coding region for the envelope glycoprotein E2 was determined (see Additional file 3) and the deduced amino acid sequences of viruses originating from cattle to goat and goat to goat infections were compared to the virus of the PI heifer. In addition, E2 amino acid sequences from viruses from the PI heifer and the initial PI goat (termed “PI goat”) that had been passaged in vitro in bovine turbinate (BT) and goat synovial membrane cells (GSM) are included. Dots represent identical amino acids. Positions of amino acid changes are highlighted by arrows. Numbering refers to the nucleotide positions as depicted in Additional file 3.