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  1. In the present study, two prospective Salmonella delivery strains, JOL2782 and JOL2837, were developed by gene deletions of lon and cpxR, which are related to cellular adhesion and intracellular survival. Additio...

    Authors: Ram Prasad Aganja, Chandran Sivasankar, Chamith Hewawaduge and John Hwa Lee
    Citation: Veterinary Research 2022 53:76
  2. Fowl adenovirus serotype 4 (FAdV-4) and FAdV-8b are causative agents of hepatitis-hydropericardium syndrome (HHS) and inclusion body hepatitis (IBH), respectively. HHS and IBH co-infections were often reported...

    Authors: Baiyu Wang, Mingzhen Song, Congcong Song, Shiyi Zhao, Panpan Yang, Qilong Qiao, Yanfang Cong, Yanling Wang, Zeng Wang and Jun Zhao
    Citation: Veterinary Research 2022 53:75
  3. Porcine reproductive and respiratory syndrome virus (PRRSV) in late gestation causes a profound suppression of circulating maternal and fetal thyroid hormone during a critical window of development. To underst...

    Authors: Erin K. Ison, Amber S. Hopf-Jannasch, John C. S. Harding and J. Alex Pasternak
    Citation: Veterinary Research 2022 53:74
  4. Pseudorabies virus (PRV) variant infections have caused a substantial economic impact on swine production in the absence of new powerful candidate vaccines. In this study, we developed and evaluated a gene-del...

    Authors: Ling Li, Yongfeng Du, Yanbin Zhang, Pengyu Li, Xinyue Liu, Xin Zhang, Jing Li, Tong Zhang, Xin Li, Dong Xiao, Peng Liu, Peng Qi and Jin Xiao
    Citation: Veterinary Research 2022 53:73
  5. Epithelial cells are known to produce mediators which can influence the behaviour of neighbouring immune cells. Although the oral mucosa has gained increased interest as a route to induce allergy desensitisati...

    Authors: Michael Pelst, Clara Höbart, Hilde de Rooster, Bert Devriendt and Eric Cox
    Citation: Veterinary Research 2022 53:72
  6. Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic debilitating disease in ruminants. To control this disease, it is crucial to understand immune evasion and th...

    Authors: Hong-Tae Park, Sang-Mok Lee, Seyoung Ko, Suji Kim, Hyun-Eui Park, Min-Kyoung Shin, Donghyuk Kim and Han Sang Yoo
    Citation: Veterinary Research 2022 53:71
  7. Bovine respiratory disease (BRD) is one of the most important diseases impacting the global cattle industry, resulting in significant economic loss. Commonly referred to as shipping fever, BRD is especially co...

    Authors: Maria Gaudino, Brandy Nagamine, Mariette F. Ducatez and Gilles Meyer
    Citation: Veterinary Research 2022 53:70
  8. Chicken cathelicidin-2 (CATH-2) as a host defense peptide has been identified to have potent antimicrobial and immunomodulatory activities. Here, we reported the mechanism by which CATH-2 modulates NLRP3 infla...

    Authors: Lianci Peng, Hongliang Tian, Yi Lu, Kaixiang Jia, Jinrong Ran, Qi Tao, Gang Li, Chao Wan, Chao Ye, Edwin J. A. Veldhuizen, Hongwei Chen and Rendong Fang
    Citation: Veterinary Research 2022 53:69
  9. Mycobacterium avium subspecies paratuberculosis (MAP) is the causative organism of Johne’s disease, a chronic granulomatous enteritis of ruminants. We have previously used naturally MAP-infected heifer calves to ...

    Authors: Emma N. Taylor, Manfred Beckmann, Glyn Hewinson, David Rooke, Luis A. J. Mur and Ad P. Koets
    Citation: Veterinary Research 2022 53:68
  10. Middle East respiratory syndrome coronavirus (MERS-CoV) poses a serious threat to public health. Here, we established an ex vivo alpaca tracheal explant (ATE) model using an air-liquid interface culture system...

    Authors: Nigeer Te, Jordi Rodon, Rhea Creve, Mónica Pérez, Joaquim Segalés, Júlia Vergara-Alert and Albert Bensaid
    Citation: Veterinary Research 2022 53:67
  11. Mycoplasma (M.) gallisepticum is the most pathogenic mycoplasma species in poultry. Infections cause mild to severe clinical symptoms associated with respiratory epithelial lesion development. Adherence, biofilm ...

    Authors: Nancy Rüger, Michael P. Szostak and Silke Rautenschlein
    Citation: Veterinary Research 2022 53:66
  12. Current strategies for porcine reproductive and respiratory syndrome (PRRS) control are inadequate and mainly restricted to immunization using different PRRS virus (PPRSV) vaccines. Although there are no safet...

    Authors: Rui Chen, Bing Liu, Xiangmei Zhang, Mengmeng Qin, Jianhui Dong, Guoqian Gu, Chunyan Wu, Jingyu Wang and Yuchen Nan
    Citation: Veterinary Research 2022 53:65
  13. Duck hepatitis A virus type 1 (DHAV-1) is one of the main pathogens responsible for death in ducklings. Autophagy is a catabolic process that maintains cellular homeostasis, and the PI3KC3 protein plays an imp...

    Authors: Juan Li, Mingshu Wang, Shan Zhou, Anchun Cheng, Xuming Ou, Di Sun, Ying Wu, Qiao Yang, Qun Gao, Juan Huang, Bin Tian, Sai Mao, Shaqiu Zhang, Xinxin Zhao, Renyong Jia, Mafeng Liu…
    Citation: Veterinary Research 2022 53:64
  14. Foot-and-mouth disease (FMD) is one of the most important livestock diseases restricting international trade. While African buffalo (Syncerus caffer) act as the main wildlife reservoir, viral and immune response ...

    Authors: Eva Perez-Martin, Brianna Beechler, Fuquan Zhang, Katherine Scott, Lin-Mari de Klerk-Lorist, Georgina Limon, Brian Dugovich, Simon Gubbins, Arista Botha, Robyn Hetem, Louis van Schalkwyk, Nicholas Juleff, Francois F. Maree, Anna Jolles and Bryan Charleston
    Citation: Veterinary Research 2022 53:63
  15. Autophagy is an important conserved homeostatic process related to nutrient and energy deficiency and organelle damage in diverse eukaryotic cells and has been reported to play an important role in cellular re...

    Authors: Yukang Wen, Zhengkun Chen, Yaqin Tian, Mei Yang, Qingshuang Dong, Yujiao Yang and Honglei Ding
    Citation: Veterinary Research 2022 53:62
  16. Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent and endemic swine pathogen which causes significant economic losses in the global swine industry. Multiple vaccines have been develope...

    Authors: Mingxin Zhang, Chunni Lu, Lizhan Su, Feixiang Long, Xia Yang, Xiaofeng Guo, Gaopeng Song, Tongqing An, Weisan Chen and Jianxin Chen
    Citation: Veterinary Research 2022 53:61
  17. Small ruminant lentiviruses (SRLV) belong to the Retroviridae family and can cause various diseases. One of the most impacting diseases is visna-maedi, a complex disease characterized by long latencies and chr...

    Authors: Riccardo Moretti, Stefano Sartore, Barbara Colitti, Margherita Profiti, Stefania Chessa, Sergio Rosati and Paola Sacchi
    Citation: Veterinary Research 2022 53:60
  18. Arginine (Arg), lysine (Lys), and methionine (Met) can be used to support the health status of turkeys. The present study investigated selected performance, gut integrity, and immunological parameters in turke...

    Authors: Paweł Konieczka, Bartłomiej Tykałowski, Katarzyna Ognik, Misza Kinsner, Dominika Szkopek, Maciej Wójcik, Dariusz Mikulski and Jan Jankowski
    Citation: Veterinary Research 2022 53:59
  19. Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the Newcastle disease virus (NDV), an important pathogen harmful to domestic poultry. Virulent NDV strain infection induces ...

    Authors: Pei Gao, Shiyuan Zhang, Xinxin Zhang, Chenggang Xu, Libin Chen, Lei Fan, Jinlian Ren, Qiuyan Lin, Bin Xiang and Tao Ren
    Citation: Veterinary Research 2022 53:58
  20. Peste des petits ruminants (PPR) is an acute disease of small ruminants caused by a morbillivirus. Clinical observation of the disease in the field revealed that several species of small ruminants are affected...

    Authors: Roger-Junior Eloiflin, Llorenç Grau-Roma, Sylvie Python, Kemal Mehinagic, Aurélie Godel, Geneviève Libeau, Artur Summerfield, Arnaud Bataille and Obdulio García-Nicolás
    Citation: Veterinary Research 2022 53:57
  21. Foot-and-mouth disease (FMD) remains a very serious barrier to agricultural development and the international trade of animals and animal products. Recently, serotype O has been the most prevalent FMDV serotyp...

    Authors: Pinghua Li, Shulun Huang, Jingjing Zha, Pun Sun, Dong Li, Huifang Bao, Yimei Cao, Xingwen Bai, Yuanfang Fu, Xueqing Ma, Kun Li, Hong Yuan, Jing Zhang, Zhixun Zhao, Jian Wang, Keqiang Zhang…
    Citation: Veterinary Research 2022 53:56
  22. Porcine reproductive and respiratory syndrome (PRRS) is a highly infectious disease caused by PRRS virus (PRRSV) that causes great economic losses to the swine industry worldwide. PRRSV has been recognized to ...

    Authors: Hong Duan, Haoxin Dong, Shuya Wu, Jiahui Ren, Mingfang Zhang, Chuangwei Chen, Yongkun Du, Gaiping Zhang and Angke Zhang
    Citation: Veterinary Research 2022 53:55
  23. The Shadoo and PrP prion protein family members are thought to be functionally related, but previous knockdown/knockout experiments in early mouse embryogenesis have provided seemingly contradictory results. I...

    Authors: Andrea Rau, Bruno Passet, Johan Castille, Nathalie Daniel-Carlier, Alexandre Asset, Jérome Lecardonnel, Marco Moroldo, Florence Jaffrézic, Denis Laloë, Katayoun Moazami-Goudarzi and Jean-Luc Vilotte
    Citation: Veterinary Research 2022 53:54
  24. Duck Tembusu virus (DTMUV) is a pathogenic flavivirus that has caused enormous economic losses in Southeast Asia. Our previous study showed that DTMUV could induce duck embryo fibroblast (DEF) apoptosis, but t...

    Authors: Yuhong Pan, Wenjun Cai, Anchun Cheng, Mingshu Wang, Shun Chen, Juan Huang, Qiao Yang, Ying Wu, Di Sun, Sai Mao, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Qun Gao, Xumin Ou…
    Citation: Veterinary Research 2022 53:53
  25. In broiler breeders, background mortality is rarely addressed, however, it represents the death of a vast number of birds, a constant productivity loss, welfare concerns and it might affect chick quality. The ...

    Authors: Sofie Kromann, Sharmin Baig, Marc Stegger, Rikke Heidemann Olsen, Anders Miki Bojesen, Henrik Elvang Jensen and Ida Thøfner
    Citation: Veterinary Research 2022 53:52
  26. Bacterial biofilms are structured clusters of bacterial cells enclosed in a self-produced polymer matrix that are attached to a biotic or abiotic surface. This structure protects bacteria from hostile environm...

    Authors: Mario Jacques and François Malouin
    Citation: Veterinary Research 2022 53:51
  27. Humans can become infected with hepatitis E virus (HEV) by consumption of undercooked pork. To reduce the burden of HEV in humans, mitigation on pig farms is needed. HEV is found on most pig farms globally, ye...

    Authors: Marina Meester, Martijn Bouwknegt, Renate Hakze-van der Honing, Hans Vernooij, Manon Houben, Sophie van Oort, Wim H. M. van der Poel, Arjan Stegeman and Tijs Tobias
    Citation: Veterinary Research 2022 53:50
  28. Avian leukosis virus subgroup J (ALV-J) can cause neoplastic diseases in poultry and is still widely prevalent in China. Chicken telomerase reverse transcriptase (chTERT) is the core component of telomerase, w...

    Authors: Yong Xiang, Qinxi Chen, Qingbo Li, Canxin Liang and Weisheng Cao
    Citation: Veterinary Research 2022 53:49
  29. Cathepsin L is an important cysteine protease, but its function in T. spiralis remains unclear. The aim of this research was to explore the biological characteristics of T. spiralis cathepsin L (TsCatL) and its r...

    Authors: Ruo Dan Liu, Xiang Yu Meng, Chen Le Li, Shao Rong Long, Jing Cui and Zhong Quan Wang
    Citation: Veterinary Research 2022 53:48
  30. The present study investigates the pathogenicity of two recently isolated strains of Suid herpesvirus 1 (SuHV1), the Greek strain Hercules and the Chinese strain HeN1, in unvaccinated pigs and in pigs vaccinat...

    Authors: Konstantinos V. Papageorgiou, Margarita Michailidou, Ioannis Grivas, Evanthia Petridou, Efthymia Stamelou, Konstantinos Efraimidis, Lei Chen, Trevor W. Drew and Spyridon K. Kritas
    Citation: Veterinary Research 2022 53:47
  31. A universal vaccine protecting against multiple serotypes of Streptococcus suis is urgently needed to improve animal welfare and reduce the consumption of antibiotics. In this study, a dual antigen expression cas...

    Authors: Yu-an Li, Yanni Sun, Yang Fu, Yuqin Zhang, Quan Li, Shifeng Wang and Huoying Shi
    Citation: Veterinary Research 2022 53:46
  32. Bovine paratuberculosis is an endemic disease caused by Mycobacterium avium subspecies paratuberculosis (Map). Map is mainly transmitted between herds through movement of infected but undetected animals. Our obje...

    Authors: Floor Biemans, Jamie Tratalos, Sandie Arnoux, George Ramsbottom, Simon J. More and Pauline Ezanno
    Citation: Veterinary Research 2022 53:45
  33. Heterologous prime-boost vaccination with experimental or commercial influenza vaccines has been successful in various animal species. In this study, we have examined the efficacy of alternating 3 different Eu...

    Authors: Anna Parys, Elien Vandoorn, Koen Chiers and Kristien Van Reeth
    Citation: Veterinary Research 2022 53:44
  34. Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the H9N2 avian influenza virus (H9N2 virus) has been clustered into multiple lineages, and its rapidly ongoing evolution incr...

    Authors: Rui Zhu, Shunshun Xu, Wangyangji Sun, Quan Li, Shifeng Wang, Huoying Shi and Xiufan Liu
    Citation: Veterinary Research 2022 53:43
  35. This article focuses on the pathogenic significance of Helicobacter species naturally colonizing the stomach of dogs, cats and pigs. These gastric “non-Helicobacter (H.) pylori Helicobacter species” (NHPH) are le...

    Authors: Emily Taillieu, Koen Chiers, Irina Amorim, Fátima Gärtner, Dominiek Maes, Christophe Van Steenkiste and Freddy Haesebrouck
    Citation: Veterinary Research 2022 53:42
  36. Little is known about how co-infections and genotype dynamics affect Mycoplasma hyopneumoniae infection in fattening pigs. This study was aimed at assessing the role of co-infections in M. hyopneumoniae outbreaks...

    Authors: Matteo Tonni, Nicoletta Formenti, M. Beatrice Boniotti, Flavia Guarneri, Federico Scali, Claudia Romeo, Paolo Pasquali, Maria Pieters, Dominiek Maes and Giovanni L. Alborali
    Citation: Veterinary Research 2022 53:41
  37. Edwardsiella piscicida is a Gram-negative enteric pathogen that causes hemorrhagic septicemia in fish. The type III secretion system (T3SS) is one of its two most important virulence islands. T3SS protein EseJ in...

    Authors: Long Kun Wang, Shan Shan Sun, Shu Ya Zhang, Pin Nie and Hai Xia Xie
    Citation: Veterinary Research 2022 53:40
  38. Lawsonia intracellularis is the causative agent of proliferative enteropathy. While it harbors genes encoding the entire apparatus required for the type III secretion system (T3SS) and the expression of some of t...

    Authors: Cang Chen, Yimin Dai, Yingying Yang, Zihe Zhu, Qinghua Zhang, Xuejiao An and Fenju Lai
    Citation: Veterinary Research 2022 53:39
  39. Environmental transmission of Chlamydia abortus as a result of enzootic disease or disease outbreaks and the threats posed by this pathogen has been previously reported, however a state-of-the-science review of t...

    Authors: Lauretta Turin, Sara Surini, Nick Wheelhouse and Mara Silvia Rocchi
    Citation: Veterinary Research 2022 53:37
  40. Th9 cells have been shown to play crucial roles in anti-parasite immunity, pathogenic microbe infection, and allergy. Previous studies have demonstrated that Haemonchus contortus excretory and secretory proteins ...

    Authors: Meng Liang, Mingmin Lu, Muhammad Tahir Aleem, Yang Zhang, Mingyue Wang, Zhaohai Wen, Xiaokai Song, Lixin Xu, Xiangrui Li and Ruofeng Yan
    Citation: Veterinary Research 2022 53:36
  41. Infection with Salmonella Typhimurium (S. Typhimurium) is a common cause of food-borne zoonosis leading to acute gastroenteritis in humans and pigs, causing economic losses to producers and farmers, and generatin...

    Authors: Juber Herrera-Uribe, Sara Zaldívar-López, Carmen Aguilar, Carmen Entrenas-García, Rocío Bautista, M. Gonzalo Claros and Juan J. Garrido
    Citation: Veterinary Research 2022 53:35
  42. Duck Tembusu virus (DTMUV), a member of the family Flaviviridae and an economically important pathogen with a broad host range, leads to markedly decreased egg production. However, the molecular mechanism underly...

    Authors: Yuhong Pan, Xuedong Wu, Wenjun Cai, Anchun Cheng, Mingshu Wang, Shun Chen, Juan Huang, Qiao Yang, Ying Wu, Di Sun, Sai Mao, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Qun Gao…
    Citation: Veterinary Research 2022 53:34
  43. Autophagy has been demonstrated to play important roles in the infection and pathogenesis of many viruses. We previously found that porcine parvovirus (PPV) infection can induce autophagy in porcine placental ...

    Authors: Xiujuan Zhang, Peipei Ma, Ting Shao, Yingli Xiong, Qian Du, Songbiao Chen, Bichen Miao, Xuezhi Zhang, Xiaoya Wang, Yong Huang and Dewen Tong
    Citation: Veterinary Research 2022 53:33
  44. The NF-κB pathway is an essential signalling cascade in the defence against viral infections, including African swine fever virus (ASFV) infection. ASFV encodes more than 151 proteins via its own transcription...

    Authors: Huan Chen, Zhenzhong Wang, Xiaoyu Gao, Jiaxuan Lv, Yongxin Hu, Yong-Sam Jung, Shanyuan Zhu, Xiaodong Wu, Yingjuan Qian and Jianjun Dai
    Citation: Veterinary Research 2022 53:32
  45. Trained immunity is the capacity of innate immune cells to produce an improved response against a secondary infection after a previous unrelated infection. Salmonellosis represents a public health issue and af...

    Authors: Rita Vaz-Rodrigues, Elisa Ferreras-Colino, María Ugarte-Ruíz, Michele Pesciaroli, Jobin Thomas, Teresa García-Seco, Iker A. Sevilla, Marta Pérez-Sancho, Rafael Mateo, Lucas Domínguez, Christian Gortazar and María A. Risalde
    Citation: Veterinary Research 2022 53:31
  46. Avian pathogenic Escherichia coli (APEC) is a pathotype of extraintestinal pathogenic E. coli and one of the most serious infectious diseases of poultry. It not only causes great economic losses to the poultry in...

    Authors: Lei Yin, Baoyan Cheng, Jian Tu, Ying Shao, Xiangjun Song, Xiaocheng Pan and Kezong Qi
    Citation: Veterinary Research 2022 53:30
  47. Interferon regulatory factors (IRFs) play a key role in many aspects of immune response, and IRF1, IRF3, and IRF7 are positive regulators of IFN induction in mammals. However, IRF3, as the most critical regula...

    Authors: Zhenyu Lin, Jie Wang, Nian Zhang, Jianshu Yi, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Kun Qian, Jianhe Sun and Yuqiang Cheng
    Citation: Veterinary Research 2022 53:29
  48. In two “départements” in the South-West of France, bovine tuberculosis (bTB) outbreaks due to Mycobacterium bovis spoligotype SB0821 have been identified in cattle since 2002 and in wildlife since 2013. Using who...

    Authors: Hélène Duault, Lorraine Michelet, Maria-Laura Boschiroli, Benoit Durand and Laetitia Canini
    Citation: Veterinary Research 2022 53:28
  49. With a worldwide distribution, Eimeria spp. could result in serious economic losses to the poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines against Eimeria spp. in food...

    Authors: ZhengQing Yu, SiYing Chen, JianMei Huang, WenXi Ding, YuFeng Chen, JunZhi Su, RuoFeng Yan, LiXin Xu, XiaoKai Song and XiangRui Li
    Citation: Veterinary Research 2022 53:27

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