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Table 1 Mean (± SEM) of immune cell infiltration scores on placentomes collected from N. caninum -inoculated (“challenged”) and negative control (“control”) dams in early, mid and late gestation

From: Inflammatory infiltration into placentas of Neospora caninum challenged cattle correlates with clinical outcome of pregnancy

Cell type

Early gestation

Mid gestation

Late gestation

Control

Challenged (SC + IV)

Control

Challenged

Control

Challenged

n

8

16

3

6

4

11

CD68+

1.79 (± 0.17)a

2.83 (± 0.16)b,A

0.87 (± 0.13)a

2.07 (± 0.20)aAB

1.25 (± 0.07)a

1.80 (± 0.08)aB

CD3+

1.15 (± 0.06)a

2.94 (± 0.12)bA

0.43 (± 0.12)a

2.12 (± 0.21)bAB

0.25 (± 0.07)a

0.87 (± 0.08)bB

CD4+

0.96 (± 0.09)a

2.49 (± 0.15)bA

0.37 (± 0.11)a

1.70 (± 0.25)aAB

0.15 (± 0.06)a

0.44 (± 0.06)aB

CD8+

0.46 (± 0.09)a

1.13 (± 0.07)bA

0.20 (± 0.11)a

0.77 (± 0.10)aAB

0.08 (± 0.04)a

0.20 (± 0.04)aB

γδTCR+

0.83 (± 0.07)a

1.39 (± 0.06)bA

0.17 (± 0.06)a

1.17 (± 0.08)bA

0.25 (± 0.07)a

0.63 (± 0.05)bB

NKp46+

0.83 (± 0.07)a

1.12 (± 0.06)bA

0.20 (± 0.10)a

0.87 (± 0.06)bAB

0.35 (± 0.09)a

0.88 (± 0.04)bB

CD79αcy+

0.96 (± 0.04)a

0.92 (± 0.05)aA

1.07 (± 0.07)a

1.20 (± 0.07)aB

0.96 (± 0.02)a

0.96 (± 0.02)aA

  1. n: number of animals per group.
  2. a,bDifferent lowercase superscript letters indicate statistically significantly different infiltration scores between control negative and N. caninum-inoculated dams (Mann–Whitney test) in each experiment (early, mid and late gestation) (p ≤ 0.05).
  3. A,BDifferent uppercase superscript letters indicate statistically significantly different overall infiltration scores for each cell marker between N. caninum-inoculated dams in early, mid and late gestation (Kruskal-Wallis test) (p ≤ 0.05).