Figure 4From: A live attenuated Salmonella Enteritidis secreting detoxified heat labile toxin enhances mucosal immunity and confers protection against wild-type challenge in chickens Relative intestinal SIgA levels in immunized birds. SIgA antibodies produced against the SE outer membrane protein antigens were measured using indirect ELISA. Bird groups were inoculated with: A, PBS control; B, JOL1087 and C, JOL1641. A Bird groups immunized via oral route. At the second week post-immunization, Group C birds showed significant rises in SIgA levels as compared to the other groups. B Bird groups immunized via the intramuscular route. At the first week post-immunization, Group C birds showed significant increases in SIgA. Birds in Group C showed consistent increases in SIgA levels 2, 3 and 4 weeks post-immunization. *Significant difference compared to the other groups (P ≤ 0.05).Back to article page