Mouse strain | Inoculum | RT-QuICa | IHCb | WBc |
---|
Tg66 | Elk-2 | 2/17 | 0/13 | 0/11 |
Tg66 | MD-1 | 0/18 | 0/8 | 0/2 |
Tg66 | WTD-1 | 2/15 | 0/14 | 0/3 |
Tg66 | None | 0/14 | 0/6 | 0/3 |
TgRM | Elk-2 | 0/14 | 0/7 | 0/3 |
TgRM | MD-1 | 0/13 | 0/9 | 0/2 |
TgRM | WTD-1 | 0/11 | 0/9 | 0/3 |
TgRM | None | 0/4 | 0/3 | 0/1 |
- aThe number of RT-QuIC mice with results significantly different than uninfected controls is shown over the total number of mice screened from the group.
- bThe number of mice positive for neuropathology including abnormal prion protein accumulation, spongiform degeneration and astrogliosis over the number tested.
- cThe number of mice that were positive for PrPres in brain by immunoblot over the number tested.