Figure 4From: Host-range shift of H3N8 canine influenza virus: a phylodynamic analysis of its origin and adaptation from equine to canine hostML tree of the H3N8 CIV concatenated full genome. From the dataset of the 44 full viral genome sequences, after splicing for segments M and NS, the segments were concatenated (HA, M1, NA, NP, NS1, PA, PB1, and PB2) for each virus, followed by the generation of a maximum-likelihood (ML) tree. The tree was constructed using the HKY + gamma nucleotide substitution model with 1000 bootstrap replications. Insert: Regression analysis of branch-length to year of virus isolation. Colour rectangles indicate different clades: clade I (yellow), clade II (pink), clade III (brown), clade IV (blue), clade V (green), clade VI (purple).Back to article page