Figure 10

Western blotting analysis of STAT6 inhibitor abrogating rTsDPP1-induced M2 polarization. Mouse peritoneal macrophages were pretreated with a STAT6 inhibitor (AS1517499) and cultured with rTsDPP1 at 37 °C and 5% CO₂ for 24 h. A Western blotting of the expression of p-STAT6, STAT6, PPARγ and Arg1 in macrophages pretreated with a STAT6 inhibitor. Tubulin served as the internal control. B The intensity of p-STAT6, STAT6, PPARγ and Arg1 protein relative to the tubulin intensity. *P < 0.05 compared to the PBS group, ^#P < 0.05 between two groups.