Figure 16

The killing effect of ADCC on NBL by rTsDPP1-treated peritoneal macrophages. Peritoneal macrophages were collected from normal BALB/c mice, pretreated with a STAT6 inhibitor (AS1517499, 100 nM) or a PPARγ antagonist (GW9662, 10 µM) for 24 h, incubated with rTsDPP1 for 24 h, and finally incubated with NBL (50 larvae/well) for 72 h. The ADCC assay was performed using infection serum (1:100) and observed by microscopy. Scale bars: 25 μm.