Table 1 Genotypic and allelic frequencies for polymorphic sites of the horse PRNP gene. Hardy–Weinberg Equilibrium (HWE). A: Alanine, G: Glycine, T: Threonine, C: Cysteine.
Polymorphisms/Breed | Genotype frequencies | Allele Frequencies | HWE (P value) | |||
|---|---|---|---|---|---|---|
c.−3A>G | AA | AG | GG | A | G | |
Thoroughbred (N = 48) | 0.98 | 0 | 0.02 | 0.98 | 0.02 | < 0.00001 |
Pura raza española (N = 30) | 0.97 | 0.03 | 0 | 0.98 | 0.02 | 0.98 |
Jaca Navarra (N = 21) | 0.95 | 0.05 | 0 | 0.98 | 0.02 | 0.98 |
Italian Trotter (N = 5) | 0.80 | 0.20 | 0 | 0.90 | 0.10 | – |
c.5T>G | TT | TG | GG | T | G | |
Thoroughbred (N = 48) | 0.96 | 0.04 | 0 | 0.98 | 0.02 | 0.98 |
c.237T>C | TT | TC | CC | T | C | |
Burguete (N = 19) | 0.80 | 0.20 | 0 | 0.90 | 0.10 | 0.80 |
Jaca Navarra (N = 21) | 0.90 | 0.10 | 0 | 0.96 | 0.04 | 0.94 |
c.301T>A | TT | TA | AA | T | A | |
Thoroughbred (N = 48) | 0.98 | 0 | 0.02 | 0.98 | < 0.00001 | |
Italian Trotter (N = 5) | 0.80 | 0 | 0.20 | 0.80 | 0.20 | – |
c.544G>A | GG | GA | AA | G | A | |
Jaca navarra (N = 21) | 0.96 | 0.04 | 0 | 0.98 | 0.02 | 0.98 |