Table 5 Evaluation of the aggregation propensities of prion protein using AMYCO.

2 V/101W/175N/182 V

0.39

Ht1 and Ht6

2 V/101W/175N/182I

0.39

–

2 V/101W/175 K/182 V

0

Ht2, Ht5, Ht7, Ht8, Ht9 and Ht11

2 V/101W/175 K/182I

0

Ht10

2 V/101R/175N/182 V

0.39

Ht13

2 V/101R/175N/182I

0.39

–

2 V/101R/175 K/182 V

0

Ht3 and Ht12

2 V/101R/175 K/182I

0.09

–

2G/101W/175N/182 V

0

Ht4

2G/101W/175N/182I

0.39

–

2G/101W/175 K/182 V

0

–

2G/101W/175 K/182I

0

–

2G/101R/175N/182 V

0.39

–

2G/101R/175N/182I

0.39

–

2G/101R/175 K/182 V

0

–

2G/101R/175 K/182I

0.09

–