Figure 3

Pasteurella multocida infection characterization in airway epithelial cells. A Schematic representation of the Pasteurella multocida infection protocol. B Scanning electron microscopy image of mouse tracheal epithelial cells infected with P. multocida (C, D) Maximal projection of confocal images for acetylated tubulin (in red), phalloidin (in green) and nucleus (in blue) in controls (C) and P. multocida infected (D) MTECs. E Volcano plot of control vs P. multocida infected MTECs. F Image obtained from STRING showing upregulated transcripts related to the NF-Kappa B and TNF signalling pathways in P. multocida infected MTECs. G, H Gene ontology analyses of upregulated (G) and downregulated (H) transcripts in P. multocida infected MTECs. Scale bar in B represents 5 μm. Scale bar in C and D represents 20 μm.